Ah at last – a good case-control with a direct head-to-head between Insulin Resistance and the great ApoB – just what the doctor ordered, n’est pas? So who will win – perhaps it will be a photo-finish, with both sharing the spoils of heart disease mayhem?
Well no – there will be a clear winner here. And one ‘also-ran’, who never even got past the first fence I’m afraid. Curious? Well see below – the 2004 paper: ‘Abnormal glucose tolerance – a common risk factor in patients with acute myocardial infarction in comparison with population-based controls’
And the final result (I’m sure you guessed right – Insulin Resistance romped home – again. We have evidence for ApoB causality, and certainly as a proxy for other issues – but balance of evidence is important too!
Oh and in case you’re thinking “maybe the lipid lowering lowered the ApoB etc etc” :
Thanks @chrimbo23 – shortening telomeres linked to cancer, CHD and damn near everything – guess what shortens ’em? http://najms.net/v03i02p057w/