This man has done amazing work, characterizing the very essence of diabetes diagnosis, and explaining why the epidemic was unstoppable: bad diagnostic medicine underpins the tragedy. He is now in his nineties, healthy no doubt due to his exceptional knowledge of hyperinsulinemia, and the huge propeortion of the modern disease landscape that is dominated by

Ok, we’ve been talking lately about Hyperinsulinemia / Insulin Resistance being one of the primary driver of the dysfunction that underpins Coronary Heart Disease and Atherosclerosis, and surmising that even the hallowed ApoB is just an interacting variable in the milieu – in other words: very low IR, then ApoB loses relevance… Anyway, these guys

Ah at last – a good case-control with a direct head-to-head between Insulin Resistance and the great ApoB – just what the doctor ordered, n’est pas? So who will win – perhaps it will be a photo-finish, with both sharing the spoils of heart disease mayhem? Well no – there will be a clear winner

Isn’t that an interesting question – especially for people who have proven Coronary Artery DIsease?  If you’ve been reading recent posts, you may take a guess at this one. Ok, I’ll put you out of hanging in suspenders there, and show you the results of this nice little study; again small sampling mathematical theory applies

Read it and weep – the decline in Coronary Artery Disease (mainly helped by smoking cessation) ended in 1994. Since then we’ve replaced Smoking with Insulin Resistance from highly-digestible carbohydrate diets. The high blood pressure is only a surrogate anyway, so reducing that after-the-fact didn’t really help much. Must act to eliminate root cause, not downstream

Well I just got my CAC score. Remember my last post where I was pseudo-devastated by a super-high Lp(a) reading? And my LDLc is damn high at ~3.5mmol/L too. We know that the Coronary CT Scan and resulting CAC score blows away all other predictors of Heart Disease, because it sees the actual disease process

No Intro needed here (warning: piece starts with a couple of echo-chamber, “exercise and moderation’  goons. Hilarious – they say that it is simplistic and wrong to “blame one macronutrient” – exactly what these dunderheads were doing for 50 years!! 🙂

Thanks @chrimbo23 for sending this one on – small numbers, but I love random pulls of peeps – they are so very unbiased and fair! Small numbers ok if the pull is represented fairly from the population, no bias (Student sorted out the math on this one out way back); this looks like a fair random sample, so

Update 27th April from George Henderson @puddleg – looks like Kraft better known than I thought! :  http://profgrant.com/2013/08/16/joseph-kraft-why-hyperinsulinemia-matters/ Oh dearie dearie me – wish Joseph R Kraft M.D. had spoken up more loudly in 1975 – read it and weep. Post-war the low-carb approach to T2 diabetes and obesity had died, and timing of this paper

From 13 minutes onwards, some of the best discussion on Cancer mechanisms I’ve seen so far – lovely gent, incredibly articulate…

Looking up ApoE4 recently, and it appears that Low Carb is extremely important for these peeps above all else – no time to discuss, but interested parties should peruse the following fascinating paper: High Carb and Alzheimer’s Disease – Ancestral Perspective Stephanie Senaff also wrote up a good ‘un in 2011: Stephanie Senaff 2011 And

Well I just hunted down a paper while researching Insulin / C-peptide as causal culprits for CHD, and this one is a zinger (all the way from 1990):   http://www.ncbi.nlm.nih.gov/pubmed/8352181 C-Peptide is important because when you provoke a molecule of insulin (i.e. carb too high, & protein somewhat – NOT fat), it comes from a pro-insulin molecule,

This is a short doc created for the premiere of the Widowmaker Movie – open your eyes peeps. Any questions on the content can be posted here, and I will endeavor to answer them. Get the test, take action – Low Carb is pivotal, Vit D, w3 and Magnesium and other things are important too; some druggery

And no, I’m not getting a cut ! Andreas has been producing excellent material to enable people achieve health and vitality (using proper medical  science). Now he has taken the plunge, built a team, and dropped the day job to enable more comprehensive content and more reach. LCHF will be the big story of the next decade, as

Thanks to Michael Eades for forwarding this accessible talk – a lovely and smart lady indeed; share it with family…

Update 26th April: Nice article from the great William Davis: http://www.cureality.com/blog/post/2012/08/08/i-wish-i-had-lipoproteina.html UPDATE 23rd April:  Ok I’ve come in with Lp(a) of ~170nMol/L. But more study and it looks like my Lp(a) top quintile only matters for ultra-high LDLc peeps (!) – Below from 2004 Physicians’ Health Study looking at Lp(a) – I’m in the nice,

Thanks to Aseem Malhotra for facebooking this on today – watched it tonight, impressive stuff. Ironies abound, as you can imagine. Enjoy it…….and send it on to others! First half:  http://www.dailymotion.com/video/x2hw4rh Second half:  http://www.dailymotion.com/video/x2hw9yw  

Well, I see today that my better half is taking a shot at the title – and will undoubtedly win 🙂 Her latest Blood Tests arrived, after a year of LCHF leverage – and wow are they saucy! Just a reminder on the absurdity of total cholesterol being even looked at (although doctors here still

Not sure if I circulated this one before, but here we go anyway. Ok, so it focuses on the old glycemic index and load – but it gives a very elegant exposure-response for inflammatory carb and CHD; also, they have corrected for a host of standard confounders, including the classic risk factor milieu. Paper below: http://nutrigen.ph.ucla.edu/files/view/pubs/00diet-carb-chd-women.pdf Note the risk

Well worth a watch – have they been squandering decades treating cancer as a genetic disease, rather than a metabolic one? Have they misconstrued this utterly, like we know they have for Fat versus Carbohydrate? Seems like they’ve done it again – the money dictates the method, again and again. Also, for anyone affected by cancer,

Great job taking apart the latest Ornish Looneybin fat-phobic nuttery – go Nina! http://thebigfatsurprise.com/critique-dean-ornish-op-ed/ Michael Eades took a swipe also – hard to resist slapping such an annoying plant-puppet 🙂 http://www.proteinpower.com/drmike/low-carb-diets/dr-dean-ornish-blasts-high-protein-diets/

Watched this last night, link from (Wyant thanks). Well made and thought provoking. Three highly intelligent, accomplished technical/academic types refuse to accept almost certain death within 24 months from Glioblastoma, choosing instead to strike out with an engineering approach. They research extensively on all the positive factors that could synergistically save them. Fascinatingly, they succeed with the

Ever wondered how they manage to still release reports insinuating that high fat diets somehow breach the laws of human metabolism and actually make us………..fat? We know that is absolute horsesh”t, but how is it that they inexplicably produce animal studies that support their preposterous position? Well, this article will help you to understand; liar

Delighted to see my good friend and accomplice in LCHF is taking the lead again – between helping so many achieve good health in his booming practice, facilitating and giving great talks, running a blog, and managing his worldwide network of those best-versed in the science of correct nutrition – where does he find the

Just got serum D3 today (possibly first time in my life). After a year of targeting 100-125nmol/L (40-50ng/ml) based on research, but not taking the time to get test, myself and wife finally got it. I used mainly Sun and Vit D Lamp, wife used mainly Vit D Lamp and supplements also. We were roughly estimating likely blood

No introduction needed here – excellent insights as usual from Ken; not one to miss for LCHF peeps, that’s for sure:

From Marty Kendall comes a stunning document that will help all to manage their Insulin levels. Carb is the major provoker, but keep an eye on yer protein too. As always, Fat is the king of energy sources, the cleanest burning fuel for humankind – once you keep the demon carb under control that is. I will be

Ok haven’t done anything on the old D for a while, and came across this very nice young man while looking up Multiple Sclerosis material; he is Dr. Sreeram Ramagopalan, and he has a nice little talk here with some insights. Interestingly, he exhibits the lowest P-value I think I’ve ever seen !  🙂

Recently came across this piece by Uffe Ravnskov. Coronary Vascular Disease is a hugely multi-factorial process, and anyone who suggests that they have the magic primary cause is, well, a bit of a monkey (unless they say it is Insulin provocation, in which case they have done their homework 😉 ). In short, the people who